Genetic or Pharmacologic Nrf2 Activation Increases Proteinuria in Chronic Kidney Disease in Mice
Monday, August 24th, 2020
Brittney M. Rush, Corry D. Bondi, Sean D. Stocker, Kacie M. Barry,Sarah A. Small,Jason Ong, Soma Jobbagy, Donna B. Stolz, Sheldon I. Bastacky, Dionysios, V.
Drug Testing for Residual Progression of Diabetic Kidney Disease in Mice Beyond Therapy with Metformin, Ramipril, and Empagliflozin
Monday, July 13th, 2020
Manga Motrapu, Monika Katarzyna Swiderska, Irene Mesas, Julian Aurelio Marschner, Yutian Lei, Laura Martinez Valenzuela, Jia Fu, Kyung Lee, Maria Lucia Angelotti, Giulia Antonelli, Paola
Discovery of diarylamides as novel orally active diuretics targeting urea transporters
Wednesday, June 24th, 2020
Shun Zhang, Yan Zhao, Shuyuan Wang, Min Li, Yue Xu, Jianhua Ran, Xiaoqiang Geng, Jinzhao He, Jia Meng, Guangying Shao, Hong Zhou, Zemei Ge, Guangping
NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture
Tuesday, June 23rd, 2020
Denise C. Cornelius, Olivia K. Travis, Robert W. Tramel, Marivee Borges-Rodriguez, Cedar H. Baik,Mallory Greer, Chelsea A. Giachelli, Geilda A. Tardo, Jan M. Williams “NLRP3
The Effects of Chronic Dapagliflozin Treatment on the Renal Microvasculature in a Rat Model of Type 2 Diabetes
Wednesday, June 10th, 2020
Connie Ow, Vijayakumar Sukumaran, Jennifer Ngo, Cheng Kun Du, Akihiro Fujiwara, Hirotsugu Tsuchimochi, Hiroshi Hosoda, Roger Evans, James Pearson, “The Effects of Chronic Dapagliflozin Treatment
RENINAAV Dose-Dependently Exacerbate Albumninuria and Glomerulosclerosis, and Reduce GFR in Female Uninephrectomized DB/DB Mice
Wednesday, June 10th, 2020
Mette Viberg Østergaard1, Rune Ida1, Annemarie Aarup Pedersen,Thomas Secher, Frederikke Emilie Sembach, Sebastian Tølbøl Thrane, Urmas Roostalu, Keld Fosgerau, Lisbeth N Fink, Niels Vrang, “Dose
Dose Escalating Toxicology Study of ELP-VEGF, a Novel Biologic for Renal Therapeutic Angiogenesis
Wednesday, June 10th, 2020
Gene Bidwell, Jamarius Waller, Jason Engel, Alejandro Chade, “Dose Escalating Toxicology Study of ELP-VEGF, a Novel Biologic for Renal Therapeutic Angiogenesis,” ERA-EDTA Meeting 2020, Nephrology
Early, but Not Late, Contralateral Nephrectomy Overcomes Progression to CKD After Unilateral Ischemic Injury
Wednesday, June 10th, 2020
Lies Moonen, Cristina Cuesta-Apausa, Francisco J. Lopez-Hernandez, Carlos Martinez Salgado, Patrick D’Haese, Benjamin Vervaet, “Early, but Not Late, Contralateral Nephrectomy Overcomes Progression to CKD After
Tubular Epithelial Cell Polyploidzation is Required to Survive AKI but Promotes CKD Development
Wednesday, June 10th, 2020
Letizia De Chiara, Elena Lazzeri, Maria Lucia Angelotti, Carolina Conte, Anna Julie Peired, Giulia Antonelli, Maria Elena Melica, Benedetta Mazzinghi, Laura Lasagni, Paola Romagnani, “Tubular
The urea transporter UT-A1 plays a predominant role in a urea-dependent urine-concentrating mechanism
Wednesday, June 3rd, 2020
Xiaoqiang Geng, Shun Zhang, Jinzhao He, Ang Ma, Yingjie Li, Min Li, Hong Zhou, Guangping Chen, and Baoxue Yang, “The urea transporter UT-A1 plays a
Metformin Inhibits Cyst Growth and Alters Cell Metabolism in Vitro and Improves Relevant Disease Parameters in a Hypomorphic ADPKD Mouse Model
Friday, May 22nd, 2020
Hui Li, Pei-Yin Ho, Valeria Mancino, Jessica Pham, Saman Sepehr, Biagio Saitta, Nuria M. Pastor-Soler, Kenneth R. Hallows, “Metformin Inhibits Cyst Growth and Alters Cell
Soluble (pro)renin receptor treats metabolic syndrome in mice with diet-induced obesity via interaction with PPARγ
Wednesday, April 15th, 2020
Fei Wang, Renfei Luo, Chang-Jiang Zou, Shiying Xie, Kexin Peng, Long Zhao, Kevin T. Yang, Chuanming Xu, and Tianxin Yang, “Soluble (pro)renin receptor treats metabolic
Targeted Inhibition of Gut Microbial TMAO Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease
Wednesday, April 8th, 2020
Nilaksh Gupta, Jennifer A. Buffa, Adam B. Roberts, Naseer Sangwan, Sarah M. Skye, Lin Li, Karen J. Ho, John Varga, Joseph A. DiDonato, W.H. Wilson
Intracellular Reactive Oxygen Species Mediate the Therapeutic Effect of Induced Pluripotent Stem Cells for Acute Kidney Injury
Wednesday, April 8th, 2020
Shun Wang, Xiaoyu Tian, Yijun Li, Rong Xue, Haochen Guan, Meng Lu, Huijun Xu, Zhibin Ye, Sifeng Chen, and Meng Xiang, “Intracellular Reactive Oxygen Species
Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats
Wednesday, February 26th, 2020
Kasi C McPherson, Corbin A. Shields, Bibek Poudel, Ashley C. Johnson, Lateia Taylor, Cassandra Stubbs, Alyssa Nichols, Denise C. Cornelius, Michael R Garrett, and Jan
Hemopexin deficiency promotes acute kidney injury in sickle cell disease
Tuesday, February 18th, 2020
Solomon Ofori-Acquah, Rimi Hazra, Oluwaseun O Orikogbo, Danielle Crosby, Bethany Flage, Ezekiel Bonwin Ackah, Diane Lenhart, Roderick J Tan, Dario A Vitturi, Vivian Paintsil, Ellis
The acute kidney injury to chronic kidney disease transition in a mouse model of acute cardiorenal syndrome emphasizes the role of inflammation
Tuesday, January 28th, 2020
Katsuyuki Matsushita, Turgay Saritas, Mahaba B. Eiwaz, Nicholas McClellan, Ian Coe, Wenbin Zhu, Mohammed Z. Ferdaus, Lynn Y. Sakai, James A. McCormick, Michael P. Hutchens,
Capillary rarefaction is more closely associated with CKD progression after cisplatin, rhabdomyolysis, and ischemia reperfusion-induced AKI than renal fibrosis
Sunday, January 26th, 2020
Anna Menshikh, Lauren Scarfe, Rachel Delgado, Charlene Finney, Yuantee Zhu, Haichun Yang, and Mark P de Caestecker, “Capillary rarefaction is more closely associated with CKD
Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis
Friday, January 17th, 2020
Turgay Saritas, Catherina A. Cuevas, Mohammed Z. Ferdaus, Christoph Kuppe, Rafael Kramann, Marcus J. Moeller, Jürgen Floege, Jeffrey D. Singer, James A. McCormick, “Disruption of
Glomerular filtrate proteins in acute cardiorenal syndrome
Friday, January 10th, 2020
Rumie Wakasaki, Katsuyuki Matsushita, Kirsti Golgotiu, Sharon Anderson, Mahaba B. Eiwaz, Daniel J. Orton, Sang Jun Han, H. Thomas Lee, Richard D. Smith, Karin D.
Impact of Aging on Transition of AKI to CKD
Sunday, January 5th, 2020
Myung-Gyu Kim, Jihyun Yang, Sewon Oh, Sang-Kyung Jo, “Impact of Aging on Transition of AKI to CKD,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: FR-PO089
Myeloid Ferritin Heavy Chain Protects Against Ferroptosis in Ischemic AKI
Thursday, December 26th, 2019
Laurence M. Black, Kayla R. Mccullough, Amie Traylor, Evan Boitet, Jeremie M. Lever, Stephanie Esman, Daryll R. Spangler, Abolfazl Zarjou, Alecia K. Gross, Subhashini Bolisetty,
A Novel Model of Chronic Kidney Disease in Rats: Dietary Adenine in Combination with Unilateral Nephrectomy
Monday, December 23rd, 2019
Cristina Muñoz Abellán, Sandra Mangold-Gehring, Sina Micus, Gerald Beddies, Andreas Moritz, Elke Hartmann, Waldemar Lehmann, Frank Eitner, “A Novel Model of Chronic Kidney Disease in
SMPDL3b Regulates Proteinuria in Experimental Alport Syndrome
Sunday, December 22nd, 2019
Alla Mitrofanova, Antonio M. Fontanella, Judith T. Molina David, Javier T. Varona Santos, Lorenza Macrina, George W. Burke, Sandra M. Merscher, Alessia Fornoni, “SMPDL3b Regulates
Paraoxonase 1 Regulation of Renal Inflammation and Fibrosis in CKD
Saturday, December 21st, 2019
Fatimah K. Khalaf, Chrysan J. Mohammed, Prabhatchandra Dube, Iman Tassavvor, Andrew Kleinhenz, Apurva Lad, Amira F. Gohara, Deepak K. Malhotra, Steven T. Haller, David J.
Patrolling monocytes promote the pathogenesis of early lupus-like glomerulonephritis
Friday, December 20th, 2019
Jeeba Kuriakose, Vanessa Redecke, Cliff Guy, Jingran Zhou, Ruiqiong Wu, Sirish K. Ippagunta, Heather Tillman, Patrick D. Walker, Peter Vogel, and Hans Häcker, “Patrolling monocytes
Podocyte-Specific Sialylation-Deficient Mice Serve as a Model for Human FSGS
Thursday, December 19th, 2019
Kristina M. Niculovic, Linda Blume, Henri Wedekind, Elina Kats, Iris Albers, Stephanie Groos, Markus Abeln, Jessica Schmitz, Esther Beuke, Jan H. Bräsen, Anette Melk, Mario
Time-course of sodium transport along the nephron in nephrotic syndrome: The role of potassium
Saturday, December 7th, 2019
Eva Dizin, Valérie Olivier, Charline Maire1, Olga Komarynets, Ali Sassi, Isabelle Roth, Johannes Loffing, Sophie de Seigneux, Marc Maillard, Joseph M. Rutkowski, Aurélie Edwards, Eric
AMPK Deficiency Worsens Albuminuria Post Uninephrectomy (UNX)
Friday, November 29th, 2019
Daniel Rivera, Roshan Rajani, Valeria Mancino, Parisa Rezapoor, Hamidreza Zohoorkari, Biagio Saitta, Pei-Yin Ho, Hui Li, Kenneth R. Hallows, Nuria M. Pastor-Soler, “AMPK Deficiency Worsens
Anti-Transforming Growth Factor β IgG Elicits a Dual Effect on Calcium Oxalate Crystallization and Progressive Nephrocalcinosis-Related Chronic Kidney Disease
Thursday, November 28th, 2019
Stefanie Steiger, Julia Felicitas Grill, Qiuyue Ma, Tobias Bäuerle, Jutta Jordan, Michaela Smolle, Claudia Böhland, Maciej Lech and Hans-Joachim Anders, “Anti-Transforming Growth Factor β IgG
The Distribution Profile of Anti-Sense Oligonucleotides Indicates That Proximal Tubular Targets Should Be Prioritized in Renal Disease
Saturday, November 23rd, 2019
Anna Granqvist, Lena William-Olsson, Barbro Basta, Charlotte Ericson, Pernilla Tonelius, Åsa Wåhlander, Thomas Bell, Patrik Andersson, Magnus Soderberg, Robert J. Unwin, Mark J. Anderton, Christine
Divergent effects of AKI to CKD models on inflammation and fibrosis
Friday, November 22nd, 2019
Laurence Black, Jeremie M Lever, Amie M. Traylor, Bo Chen, Zhengqin Yang, Stephanie Esman, Yanlin Jiang, Gary Cutter, Ravindra Boddu, James George, and Anupam Agarwal,
Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury
Wednesday, November 20th, 2019
Elena Lazzeri, Maria Lucia Angelotti, Anna Peired, Carolina Conte, Julian A. Marschner, Laura Maggi, Benedetta Mazzinghi, Duccio Lombardi, Maria Elena Melica, Sara Nardi, Elisa Ronconi,
Endogenous pentraxin 3 inhibits nephrocalcinosis and protects from hyperoxalluria-induced Chronic Kidney Disease
Monday, November 18th, 2019
Julian A. Marschner, Shrikant R. Mulay, Stefanie Steiger, Lidia Anguiano, Antonio Inforzato, Cecilia Garlanda, Mantovani Alberto, Hans-Joachim Anders, “Endogenous pentraxin 3 inhibits nephrocalcinosis and protects
Regulation and Role of NADPH Oxidase 4 in CKD
Monday, November 18th, 2019
Sophie M. De Seigneux, Renuga Devi Rajaram, Anna Faivre, Vasiliki Delitsikou, Vincent Jaquet, Maja Lindenmeyer, Clemens D. Cohen, “Regulation and Role of NADPH Oxidase 4
Erythropoietin induces bone marrow and plasma fibroblast growth factor 23 during acute kidney injury
Sunday, November 17th, 2019
Abdulmahdi W, Rabadi MM, Jules E, Marghani Y, Marji N, Leung J, Zhang FF, Siani A, Siskind T, Vedovino K, Chowdhury N, Sekulic M, Ratliff
Genetic Nrf2 Enhancement Increases Proteinuric Renal Injury
Friday, November 15th, 2019
Brittney M. Rush, Corry D. Bondi, Kacie Barry, Sean D. Stocker, Soma Jobbagy, Donna B. Stolz, Dionysios Chartoumpekis, Thomas W. Kensler, Roderick J. Tan, “Genetic
Kidney dysfunction in the low birth weight murine adult: implications of oxidative stress
Monday, November 11th, 2019
Toro L, Barrientos V, León P, Rojas M, Gonzalez M, González-Ibáñez A, Illanes S, Sugikawa K, Abarzúa N, Bascuñán C, Arcos K, Fuentealba C, Tong
Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats
Monday, October 28th, 2019
Chang Z. Zhu, Kelly J. Doyle, Arthur L. Nikkel, Lauren Olsen, Marian T. Namovic, Katherine Salte, Deborah Widomski, Zhi Su, Diana L. Donnelly-Roberts, Murali M.
Ubiquitin C-Terminal Hydrolase L1 is required for regulated protein degradation through the ubiquitin proteasome system in kidney
Sunday, October 27th, 2019
Victoria Rado, Maire Czesla, Julia Reichelt, Julia Fehlert, Anna Hammel, Alva Rosendahl, Jan-Hendrik Knop, Thorsten Wiech, Ulrich O. Wenzel, Marlies Sachs, Anna T. Reinicke, Rolf